Surface acoustic wave biosensor as a functional quality method in pharmaceutics

A Urinary Bcl-2 Surface Acoustic Wave Biosensor for Early Ovarian Cancer Detection

In this study, the design, fabrication, surface functionalization and experimental characterization of an ultrasonic MEMS biosensor for urinary anti-apoptotic protein B-cell lymphoma 2 (Bcl-2) detection with sub ng/mL sensitivity is presented. It was previously shown that urinary Bcl-2 levels are reliably elevated during early and late stages of ovarian cancer. Our biosensor uses shear horizont...

An interleukin-6 ZnO/SiO(2)/Si surface acoustic wave biosensor.

A novel high sensitivity ZnO/SiO(2)/Si Love mode surface acoustic wave (SAW) biosensor for the detection of interleukin-6 (IL-6), is reported. The biosensors operating at 747.7 MHz and 1.586 GHz were functionalized by immobilizing the monoclonal IL-6 antibody onto the ZnO biosensor surface both through direct surface adsorption and through covalent binding on gluteraldehyde. The morphology of t...

Surface acoustic wave biosensors: a review.

This review presents an overview of 20 years of worldwide development in the field of biosensors based on special types of surface acoustic wave (SAW) devices that permit the highly sensitive detection of biorelevant molecules in liquid media (such as water or aqueous buffer solutions). 1987 saw the first approaches, which used either horizontally polarized shear waves (HPSW) in a delay line co...

Surface Acoustic Wave Tactile Display

eveloping realistic tactile displays for virtual reality has been challenging. Tangible displays are increasingly important interfaces not only for augmenting the reality of computer graphics but also for conveying graphical information to persons with visual impairments. Researchers have used various actuators for displays such as miniature loud speakers , 1 a pin array, 2 pneumatic actuators,...

Ultrananocrystalline Diamond as Material for Surface Acoustic Wave Devices